ENDONEXT Endotoxin Detection Kits

We’re making endotoxin testing faster, easier and more ecologically friendly by mimicking nature, not exploiting it. Our kits enable confident in-process control and product release decisions of biopharmaceutical products and medical devices. Explore the ENDONEXT range of time and cost-saving solutions. 

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The ENDONEXT range of next-generation bacterial endotoxin tests developed by Hyglos - a bioMérieux company, rely on recombinant Factor C (rFC), an exact synthetic copy of the endotoxin-sensitive enzyme naturally harbored by the blood of horseshoe crabs. Our rFC methods offer enhanced specificity, flexibility, lot-to-lot consistency, a sustainable and secure source and are approved alternative methods by the Ph. Eur. chapter 5.1.10 since July 1, 2016.

Select the ideal method for your samples from the ENDONEXT range:



NEW 2018: The rapid GO version of ENDOZYME® II featuring GOPLATE™—a microplate pre-filled with required standard curve and positive product control concentrations (PPC).
• Eliminates manual preparation of standard dilutions and PPCs
• Over 50% reduction in handling time compared to conventional microplate assays
• Significantly reduces risk of error
• Ideal for in-process control of water and raw materials as well as product release testing
• Easy automation


endotoxin detectionFast and flexible Recombinant Factor C Assay.

The enhanced 2nd generation endpoint fluorescent microplate assay enables detection of as low amounts as 0.001 EU/mL.









endotoxin detection

ELISA-Based Recombinant Factor C Assay.

With its unique built-in sample preparation, the EndoLISA® endpoint fluorescent microplate assay revolutionizes endotoxin testing of complex samples.






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Pioneering diagnostics