Real-Time PCR innovative Solution for Pathogen Detection

Molecular pathogen detection has never been simpler, faster or more flexible. 

GENE-UP® offers:

  • An easy-to-use workflow
  • A wide range of throughput levels
  • An intuitive interface
  • An open platform for maximum flexibility
  • The peace of mind that comes from making confident decisions


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GENE-UP® Overview

In today’s ever-evolving food marketplace, nothing is more important than product safety. To protect your customers, your company and your reputation, you need a fast and simple method of detecting pathogens.


With GENE-UP®, you’re not just getting an intuitive, real-time PCR solution for pathogen detection, you’re getting 50 years of microbiology leadership from a vigilant team that embraces the highest standards in microbiology safety. What’s more, our dedicated Customer Support and Scientific Affairs teams will work closely with you, ensuring that you can easily take full advantage of the GENE-UP® system.

How GENE-UP® Works


Step 1: Sample Preparation and Enrichment

  • Standardized protocol and workflow
  • Single enrichment
  • Incubation time between 8-24 hours

Step 2: Simplified Lysis

  • Optimized productivity with Magic Cap
  • 5-minute mechanical lysis

    Step 3: Amplification and Detection

    • Same PCR run for all parameters
    • Accurate results within one hour
    • Higher level of specificity
    • Real-time PCR analysis coupled with end-point melt peak analysis

    GENE-UP® Benefits

    FRET technology & Melt analysis

    • Increase profitability by reducing product waste
    • Decide with confidence by lessening the number of questionable results
    • Unrivaled specificity

    Rapid results

    • Speed up your decision process
    • Improve your manufacturing efficiency
    • Decrease your storage cost
    • Increase sales profit

    Ease of use

    UNIQUE & PATENTED lysis reagent

    5 minute generic lysis step

    • Improve Productivity
    • Facilitate lab workflow
    • Manage pick of activities
    • Decrease cross contamination risk
    • No need to work in batches (i.e. Gram + & Gram – follow the same lysis step)
    • Limited training required


    • Remote routine software: Speed-up your decision process
    • Generic Lysis step: Facilitate lab organization & workflow
    • Room temperature storage
    • Open Platform: Answer to your alternative testing needs (including foodborne viruses)


    PCR detection Kits available:

    • PCR Salmonella
    • PCR  E. coli O157:H7
    • PCR  Listeria spp.
    • PCR Listeria monocytogenes
    • PCR Cronobacter spp Unit Dose




    The EHEC Kit combines stx and eae, and the top 6 serogroups in one solution. And, using GENE-UP® in combination with VIDAS®, the EHEC solution provides unrivaled specificity. Read more on our EHEC Solution



    GENE-UP® Features

    Simple to use

    • DNA extraction in 5 minutes with generic lysis step
    • Patented “Magic Cap” eliminates capping and de-capping, improving productivity
    • Room temperature storage of reagents
    • Standardized workflow and protocols
    • Superior performance

    Rapid and reliable results

    • High specificity thanks to the primers and probes of FRET technology and melt analysis
    • Internal controls in every test
    • AOAC RI validated for PCR Salmonella and PCR E. coli O157:H7
    • AOAC RI for PCR Listeria spp. and PCR Listeria monocytogenes in progress

    Maximum flexibility

    • Compatible lysis and PCR for all parameters
    • Anywhere, anytime reporting with remote, web-based software
    • Opportunity to design and run homebrew PCR tests
    • Capability to run CeeramTools foodborne viruses extended offer

    GENE-UP® Reagents

    GENE-UP® offers ready-to-use test kits for your most pressing food safety concerns. The simple workflow is the same with each test, minimizing training and improving efficiencies. Current test kits include:

    GENE UP® Salmonella (Ref. 414150), GENE UP® Cronobacter (Ref. 421920), GENE UP® Listeria spp (Ref. 414059) and GENE UP® Listeria monocytogenes (Ref. 414058) methods are NF VALIDATION validated by AFNOR Certification, according to ISO 16140-2 standard.

    GENE UP® E. coli O157 :H7 (Ref. 414152) method has been validated by Microval according to ISO 16140-2 standard.

    The scope of those methods is available from our reagent package inserts.

    The PCR Salmonella and PCR E. coli O157:H7 assays have also received AOAC Performance Tested MethodsSM certification from the AOAC Research Institute (AOAC-RI):

    • Salmonella Certificate No. 061504
    • E. coli O157:H7 Certificate No. 061505

    In addition to our test kits, GENE-UP has the flexibility to perform ceeramTOOLS kits for virus & parasire detection (duplex and simplex tests):
    Norovirus GI

    Norovirus GII
    Hepatitis A
    Hepatitis E


    GENE-UP® Software

    The GENE-UP® solution is commercialized with two different software options:

    • Routine: to use GENE-UP® tests for the detection of the pathogens of interest (Salmonella, E. coli O157:H7, Listeria spp., Listeria monocytogenes)
    • Open: to run the  CeeramTools virus kits, to create your own tests and determine your own interpretation.

    GENE-UP® routine software

    The GENE-UP® routine software is used to:

    • set up the plate map
    • check the results

    PCR detection testing kit salmonella listeria E.coli
    GENE-UP® (PCR detection kits for foodborne pathogens) routine software home page


    The GENE-UP® routine software has been designed to be accessible from any PC in the lab AND in the office!

    • You do not need to be at the bench to setup your plate map and to check your results
    • It can speed up your decision process

    To give maximum flexibility, the GENE-UP®routine software can be installed on your own PC! The software can be connected to your LIMS.



    foodborne pathogen molecular detection solution: software screenshot

    GENE-UP® routine software results page for PCR Listeria kit


    GENE-UP® Specs

    The GENE-UP® instrument can be positioned on any stable and non-moving bench. A typical installation requires workspace of: width 40” and a bench depth 24” and a clearance height of 36”.

    GENE-UP® Instrument

    Height (inches)


    Width (inches)


    Depth (inches)


    Weight (lbs.)


    Electrical Requirements


    6.5 amps @ 120 VAC

    Heat Dissipated

    2218 BTU/hr


    120 Volts

    Electrical Consumption

    20 amps


    60 Hz

    Environmental Conditions

    Temperature Range

    59°F to 86°F with no wide temperature fluctuations

    Room Relative Humidity

    10% to 8-% RH, non-condensing


    -328 to 9842 feet above sea level




    1.7 amps @120 VAC


    0.3 amps @120 VAC


    5.0 amps @120 VAC


    Please consult our local company or representatives for the availability of these products in your country

    Pioneering diagnostics