微生物関連情報

Cutibacterium Acnes

FELIX-MONTERO-JULIAN-PHD-BIOMERIEUX.jpg
by Felix MONTERO-JULIAN PhD
MOL0052007_Microorganisms Library_C.acnes_banner.png

Cutibacterium acnes

Cutibacterium acnes とは

Cutibacterium acnesは、酸素のない嫌気環境を好む、バイオフィルム形成が可能なグラム陽性桿菌1で、ほとんどのヒトの皮膚に存在し、尋常性痤瘡 (ニキビ) を引き起こす細菌のひとつである。

ニキビは最も一般的な皮膚疾患のひとつで、米国においては皮膚科を訪れる患者の約20%がニキビの治療に関するものともいわれている。

C. acnesは一般的な常在菌であるものの、術後感染やその他疾患に関与する日和見病原菌としても知られている。

以下の内容について概説しています。

  • Cutibacterium acnes による汚染の予防
  • 医薬品製造におけるCutibacterium acnes の検出
  • Cutibacterium acnes の消費者に対するリスク

本資料のダウンロードはこちらから

 

 

img6FELIX-MONTERO-JULIAN-PHD-BIOMERIEUX
Written by
Felix
MONTERO-JULIAN PhD

Scientific Director Healthcare Business
Healthcare Business Industry Unit
bioMérieux SA, France

1 Leheste, Joerg R., Ruvolo, Kathryn E., Chrostowski, Joanna E., Rivera, Kristin, Husko, Christopher, Miceli, Alyssa.,Selig, Martin K, Brüggemann, Holger and Torres, German (2017) C. acnes-Driven Disease Pathology: Current Knowledge and Future Directions. Frontiers in Cellular and Infection Microbiology March, 7 : 81, 1- 9
2 Viraraghavan R, Jantausch B, Campos J. Late-onset central nervous system shunt infections with Propionibacterium acnes: diagnosis and management. Clinical Pediatrics. 2004;43(4):393–397, Schäfer P, Fink B, Sandow D, Margull A, Berger I, Frommelt L. Prolonged bacterial culture to identify late periprosthetic joint infection: a promising strategy. Clinical Infectious Diseases. 2008;47(11):1403–1409, Butler-Wu SM, Burns EM, Pottinger PS, et al. Optimization of periprosthetic culture for diagnosis of Propionibacterium acnes prosthetic joint infection. Journal of Clinical Microbiology. 2011;49(7):2490–2495
3 Arlt, Nicole , Rothe, Remo , Sielaff, Susann , Juretzek, Thomas , Peltroch, Heidrun (2018) Sterility release testing of peripheral blood stem cells for transplantation: impact of culture bottles and incubation temperature, December Volume58, Issue12
4 Acherman, Y., Goldstein, E.J.C., Coenye, T., Shirtliff, M.E. (2014) Propionibacterium acnes: from commensal to opportunistic biogfilm-associated implant pathogen Clin. Microbio. Rev, Jul; 27(3): 419-440; Portillo, María Eugenia, Corvec, Stéphane, Borens, Olivier and Trampu, Andrej, (2013) Propionibacterium acnes: An Underestimated Pathogen in Implant-Associated Infections n BioMed Research International Volume 2013, page 1-10 Article ID 804391, 10 pages
5 Lazar JM, Schulman DS. Propionibacterium acnes prosthetic valve endocarditis: a case of severe aortic insufficiency. Clinical Cardiology. 1992;15:299–300
6 Underdahl JP, Florakis GJ, Braunstein RE, Johnson DA, Cheung P, Briggs J, Meisler DM. Propionibacterium acnes as a cause of visually significant corneal ulcers. Cornea. 2000;19:451–454
7 Thompson TP, Albright AL. Propionibacterium acnes infections of cerebrospinal fluid shunts. Childs Nervous System. 1998;14:378–380 5 Acherman, Y., Goldstein, E.J.C., Coenye, T., Shirtliff, M.E. (2014) Propionibacterium acnes: from commensal to opportunistic biogfilm-associated implant pathogen Clin. Microbio. Rev, Jul; 27(3): 419-440; Portillo, María Eugenia, Corvec, Stéphane, Borens, Olivier and Trampu, Andrej, (2013) Propionibacterium acnes: An Underestimated Pathogen in Implant-Associated Infections n BioMed Research International Volume 2013, page 1-10 Article ID 804391, 10 pages
8 Holmberg A, Lood R, Morgelin M, et al. Biofilm formation by Propionibacterium acnes is a characteristic of invasive isolates. Clin Microbiol Infect. 2009;15(8):787–9
9 https://emedicine.medscape.com/article/226337-medication
10 Csukás Z, Banizs B, Rozgonyi F. Studies on the cytotoxic effects of Propionibacterium acnes strains isolated from cornea. Microbial Pathogenesis. 2004;36(3):171–174.

 

製品・ソリューションについて、微生物検査のエキスパートから情報提供いたします。